5-hydroxytryptamine (Serotonin) Receptor 1D, 15 uL

5-hydroxytryptamine (Serotonin) Receptor 1D, 15 uL

ExpressMAX™ Expression-ready Human GPCR ORF Clones

Na objednávku
Výrobca: CANVAX
Katalógové číslo: G0613 - A

5-hydroxytryptamine (Serotonin) Receptor 1D

ExpressMAX™ Expression-ready Human GPCR ORF Clones

Product Overview:

GPCR for serotonin, found in nociceptors throughout the body. The anti-migraine action of “triptan” Drugs involves the activation of serotonin subtype 1D (HT1D) Receptors expressed on “pain-responsive” trigeminal primary afferents. HT1D Receptors are present in a similar subpopulation of trigeminal and dorsal root ganglia neurons and in the central terminals of primary afferents.

Advantages & Features

  • Native structure.
  • Wide range: A large collection of ExpressMAX™ GPCR ORF Clones availables.
  • Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry.
  • Wide spectrum: of strong constitutive promoters.
  • Complete solution: it contains all necessary elements for maximum receptor expression.
  • Ready-to-use solution: avoids cloning steps, DNA ready to transfect.
  • Easy protocol and detection: the whole procedure is simple, with minimal handling.
  • Neomycin resistance.
  • Ampicillin bacterial selection.

Specifications

  • Plasmid size: 7129 pb
  • Promoter: PEF1α
  • ORF Sequence (GenBank based): NM_012852
  • Protein Sequence (SwissProt): P28565
  • Bacterial Selection Antibiotics: Ampicillin
  • Mammalian Selection Antibiotic: Neomycin
  • Alternative names: 5HT1D
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