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ExpressMAX™ Expression-ready Human GPCR ORF Clones
5-hydroxytryptamine (serotonin) Receptor 1A
ExpressMAX™ Expression-ready Human GPCR ORF Clones
Product Overview:
It belongs to the 5-hydroxytryptamine Receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of the gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers.
Advantages & Features
- Native structure.
- Wide range: A large collection of ExpressMAX™ GPCR ORF Clones availables.
- Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry.
- Wide spectrum: of strong constitutive promoters.
- Complete solution: it contains all necessary elements for maximum receptor expression.
- Ready-to-use solution: avoids cloning steps, DNA ready to transfect.
- Easy protocol and detection: the whole procedure is simple, with minimal handling.
- Neomycin resistance.
- Ampicillin bacterial selection.
Specifications
- Plasmid size: 7242 pb
- Promoter: PEF1α
- ORF Sequence (GenBank based): NM_000524
- Protein Sequence (SwissProt): P08908
- Bacterial Selection Antibiotics: Ampicillin
- Mammalian Selection Antibiotic: Neomycin
- Alternative names: G-21, 5HT1a, PFMCD, 5-HT1A