aloquence Kategórie

Human PDGF-AB

Human PDGF-AB

https://www.peprotech.com/en-GB/Pages/Product/100-00AB
Na sklade 1 ks
Výrobca: PEPROTECH
Katalógové číslo: 100-00AB-2uG
1 Položka
Posledné kusy v sklade
73,13 €
S DPH
60,94 € bez DPH

PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet alfa-granules, and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-alfa and PDGFR-beta. PDGFR-alfa is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB.
Produkt bol pridaný do zoznamu prianí